College Football Week 4 odds and betting lines. Includes updated point spreads, money lines and totals lines. The picks and predictions from the experts for the biggest Week 4 college football games. College football Week 4 predictions for big games. Remember this — these aren't necessarily matchups we'd normally play at the window each week either. These are 10 of the top games across. After a mild week three in college football, the Week 4 slate delivers some massive matchups that will directly impact the national championship race. This week’s college football slate is the.

1. Week 4 College Games
2. Week 4 College Football Games On Tv
3. Biggest College Games This Weekend
4. Week 4 College Football Spreads

2019 College Football Week 4 Free Predictions and Picks Against the Spread September 16, 2019 30A Sports Picks 0 Use the Matchup generator above to analyze all games by comparing the offensive ratings for each unit versus the opposing defensive unit.

Week 4 of the college football season is here, and we're coming off a hot week against the spread. This week's biggest challenges are the top 25 matchups between No. 22 Texas A&M and No. Can Texas A&M threaten No. Will Stanford or Oregon take the lead in the Pac-12 North? Our experts pick those Week 4 games and more.

Week 4 of the college football season is here, and we're coming off a hot week against the spread.

This week's biggest challenges are the top 25 matchups between No. 22 Texas A&M and No. 1 Alabama and the primetime matchup between No. 7 Stanford and No. 20 Oregon. Those are the biggest pieces in the College Football Playoff heading into the week. With that in mind, Sporting News has picks against the spread for all the Top 25 games.

MORE: Michigan-Nebraska: The greatest game never played

Here is a look at our record so far:
Straight up: 53-9, .854 (15-4 last week)
Against the spread: 29-20, .592 (11-6 last week)

Here are our picks against the spread for Week 4 (odds reflect consensus picks from VegasINsiders.com as of Sept. 18):

Friday, Sept. 21

FAU at No. 16 UCF (-13.5)
8 p.m., ESPN
This might be the most entertaining game of the weekend. FAU can score, and Devin Singletary already has seven touchdown runs this season. The Knights might need a quarter to shake off some rust, but McKenzie Milton will lead a fourth-quarter touchdown drive that seals the victory. UCF wins 42-34 but FAILS TO COVER the spread.

No. 10 Penn State (-28) at Illinois
9 p.m., Fox Sports 1
Illinois has improved under third-year coach Lovie Smith, and the Friday primetime spotlight is a unique opportunity. Penn State, however, uses that stage to get Ohio State's attention with an offense that's blossoming around star quarterback Trace McSorley. It plays out right on the line. Penn State wins 42-16 but FAILS TO COVER the spread.

Saturday, Sept. 22

No. 2 Georgia (-14.5) at Missouri
Noon, ESPN

Big spot for the Tigers. Drew Lock ranks second among Power 5 quarterbacks with 11 passing touchdowns, and the high-powered offense can put up points. The Bulldogs are 5-1 in this series since Mizzou joined the SEC, and they rolled up 696 yards of offense in this game last season. It might take a half, but the Bulldogs pull away. Georgia wins 41-20 and COVERS the spread.

No. 8 Notre Dame (-7.5) at Wake Forest
Noon, ABC
The Irish haven't exactly dominated their last two opponents, and that will give the Demon Deacons confidence, at least, that they can pull the upset at home. If Brandon Wimbush can't have success in the air against a pass defense that allows 310.7 yards per game, however, then the Irish might get into some trouble. Notre Dame wins 33-19 and COVERS the spread.

Nebraska at No. 19 Michigan (-18.5)
Noon, FS1
Both teams might be missing playmakers. Nebraska quarterback Adrian Martinez (knee) is questionable. Michigan running backs Karan Higdon and Chris Evans are “day-to-day.” We're a long from 1997 with these two teams, but the Wolverines get this one. Michigan wins 27-17 but FAILS TO COVER the spread.

MORE: Week 4 bowl projections

No. 23 Boston College (-6.5) at Purdue
Noon, ESPN2
The Eagles are in the position Purdue was hoping to be in at this point in the season. AJ Dillon averages 7.3 yards per carry, and BC ranks sixth in the FBS with 52.7 points per game. Purdue allows 30.3 points per game, but they've lost three games by seven points. It's another shootout, and this time the Boilermakers get one in the “W” column. Purdue wins 41-38 in an UPSET.

No. 22 Texas A&M at No. 1 Alabama (-27)
3:30 p.m., CBS
Given the way Alabama has scorched opponents the first three weeks, it might seem like a reach to pick somebody to cover against that offensive machine. The Aggies, however, also are 3-0 against the spread and have the lost the last three meetings by an average of 15 points per game. Alabama wins 38-14 but FAILS TO COVER the spread.

No. 3 Clemson (-17) at Georgia Tech
3:30 p.m., ABC
The Tigers should be prepared for the option attack, given they've seen Furman and Georgia Southern already this season. The Yellow Jackets have their backs against the wall after back-to-back losses to South Florida and Pitt, but Clemson is a legit road warrior now. Expect more of the same. Clemson wins 42-20 and COVERS the spread.
Tulane at No. 4 Ohio State (-35.5)
3:30 p.m., Big Ten Network
Urban Meyer's should provide a jolt for the Buckeyes at home, and Tulane is the last tune-up before the showdown at Penn State. Senior quarterback Jonathan Banks has protected the ball for the Green Wave through three weeks and Nick Bosa (groin) won't play, but that won't matter. Ohio State wins 52-14 and COVERS the spread.
No. 13 Virginia Tech (-27.5) at Old Dominion
3:30 p.m. CBS Sports Network
The Monarchs will play with nothing to lose given their 0-3 start, but that probably won't matter. Virginia Tech had an extra week off due to Hurricane Florence, and ODU is tied for 109th in scoring defense. Look for the Hokies' to put up big numbers on the ground. Virginia Tech wins 48-10 and COVERS the spread.

MORE: Week 4 Playoff picture
Kansas State at No. 12 West Virginia (-16)
3:30 p.m., ESPN
The Wildcats have split the last two meetings in Morgantown — games that were decided by a total of seven points. West Virginia had an extra week to prepare, however, and Will Grier will be ready. Watch the third quarter, where the Mountaineers average 20.5 points. West Virginia wins 45-23 and COVERS the spread.
FIU at No. 21 Miami (-26.5)
3:30 p.m., ESPN2
Butch Davis gets a crack at his former team, and the Golden Panthers average 39.7 points per game. Miami bounced back after the season-opening loss to LSU, and the Hurricanes' rushing attack will pile up the yards here. We like FIU with the back-door cover. Miami wins 48-23 but FAILS TO COVER the spread.
No. 17 TCU (-3) at Texas
4:30 p.m., FOX
There's temptation to take Texas here knowing the Longhorns are coming off a season-saving win against USC, coupled with a potential TCU hangover from the Ohio State loss. The Horned Frogs, however, have the more dynamic quarterback in Shawn Robinson. TCU also is the only Big 12 team that beat the Longhorns by double digits last season. TCU wins 34-24 and COVERS the spread.
McNeese at No. 25 BYU (No line)
6 p.m., BYTV
BYU is ranked on the strength of their upset against Wisconsin, and this will be the first chance to pour on the points after a brutal slate to start the season, which included Arizona, Cal and the Badgers. There's a small risk for an emotional letdown, but the Cougars can handle success. BYU wins 44-14 with no spread.
Army at No. 5 Oklahoma (-31.5)
7 p.m., ppv
Army piles up the rushing yards — they average 306.7 yards per game. That will test the Sooners' patience on defense if the Black Knights can hang around in the first half. Kyler Murray, however, is a problem they won't be able to solve. We still like the cover here. Oklahoma wins 40-10 and FAILS TO COVER the spread.

MORE: Week 3 overreactions
Louisiana Tech at No. 6 LSU (-20.5)
7 p.m., TBD
Louisiana Tech is 2-0 under Skip Holtz and had an extra week to prepare for an LSU team coming off an emotional victory at Auburn. Tailback Jaquis Dancy averages 10.6 yards per carry with four touchdowns on the season. That said, the Tigers pull away in the second half. LSU wins 38-20 and FAILS TO COVER the spread.
No. 14 Mississippi State (-10) at Kentucky
7 p.m., ESPN2
This is an opportunity for Kentucky to go to 4-0, and the two-pronged rushing attack of running back Benny Snell and quarterback Terry Wilson can help the Wildcats control the clock. The Bulldogs can do the same with Nick Fitzgerald and Kylin Hill. This has the potential to be the most exciting game of the weekend as a result. Perhaps Mississippi State gets caught looking ahead to Florida? Kentucky wins 37-34 in an UPSET.
Texas Tech at No. 15 Oklahoma State (-13)
7 p.m., FS1
Oklahoma State is climbing up the polls, and with good reason after a beatdown of formerly ranked Boise State. The Cowboys have won the last nine meetings against the Red Raiders, and as you can imagine, most those games have been shootouts. The Red Raiders allow 32 points per game. Oklahoma State wins 55-38 and COVERS the spread.
No. 24 Michigan State (-4.5) at Indiana
7:30 p.m., BTN
It's tempting to take Indiana here given the Hoosiers' hot start, coupled with the fact they won the last meeting in Bloomington and hung around in East Lansing last year. Michigan State, however, had a week to refocus after the bye week. We expect the Spartans to play with more urgency now. Michigan State wins 34-24 and COVERS the spread.

Arkansas at No. 9 Auburn (-29.5)
7:30 p.m., SEC Network
Auburn is back home after a demoralizing loss to LSU, and this will be a test of focus for Jarrett Stidham and the offense. Arkansas is off to a 1-2 start under first-year coach Chad Morris but capitalize in the first half before reality sets in. Auburn wins 44-14 and COVERS the spread.

Week 4 College Games

MORE: SN updated Power Rankings
No. 7 Stanford (-2) at No. 20 Oregon
8 p.m., ABC
These Pac-12 rivals meet again, and it's the classic offense vs. defense matchup we've been used to for the last decade. Oregon averages 51.7 points per game, and the Cardinal lead the nation in scoring defense (7.7 ppg). The expected return of Bryce Love should help, too. Stanford wins 30-27 and COVERS the spread.
No. 18 Wisconsin (-3.5) at Iowa
8:30 p.m., FOX
Iowa has a chance to seize control of the Big Ten West in the always-electric environment at Kinnick Stadium. The defense has allowed just 8.0 points per game. Wisconsin, however, has won the last four in Iowa City and plays with a little more edge after the loss to BYU. Jonathan Taylor scores the game-winning touchdown in the final minutes. Wisconsin wins 24-17 and COVERS the spread.
Arizona State at No. 10 Washington (-17.5)
10:30 p.m., ESPN
Washington lost to the Sun Devils on the road last season, and the Huskies allow just 10.3 points per game. The Sun Devils have won 11 of the last 12 meetings dating back to 2002, but this won't be one of them. Washington wins 30-14 but FAILS TO COVER the spread.

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Finally, a weekend worth being excited about this season in college football.

After consecutive ho-hum Saturdays filled with less-than-ideal matchups, there's several Top 25 showdowns in Week 5, including Notre Dame's prime-time extravaganza at Georgia. Could the Irish swing momentum on their side and join LSU with notable road victories over elite competition?

Michigan-Wisconsin is another good on good tilt this weekend as Jim Harbaugh tries to establish a new narrative as the Wolverines' head coach against a top team. Michigan has struggled offensively through two weeks and the Badgers haven't given up a point yet.

Something's got to give in an early glimpse at two of the Big Ten's top teams behind Ohio State.

After a perfect 10-0 week straight up, Chris has taken a five-game edge over me in the picks department and we're both making you money in the much tougher against the spread selection. Remember this — these aren't necessarily matchups we'd normally play at the window each week either. These are 10 of the top games across college football and we're giving out leans, regardless.

Where we stand after Week 3: Brad Crawford — Straight up: 20-10; Against the spread: 17-13; Chris Hummer — Straight up: 25-5; ATS: 17-13.

Onto this week's picks for Week 4's biggest games ..

Week 4 College Football Games On Tv

Hummer: Utah as a 3.5-point favorite seems generous to USC. The idea of transitive property is a flawed, but I can’t help note BYU just beat USC in overtime. That’s the same Cougars team that lost by 18 to the Utes in Week 1. I can see a scenario in which Utah gets in a shootout and loses – scoring in bunches is not Utah’s strength – but here’s to betting USC’s true freshman QB has fits with the Utes’ defense. … Utah 27, USC 20.

Crawford: The Pac-12's last hope as far as the College Football Playoff is concerned, Utah is a Top 10 team in my opinion and will show that on Saturday vs. a talent-rich USC squad. Back-to-back losses for the Trojans puts Clay Helton squarely on the hot seat as the buzz surrounding his future continues. .. Utah 26, USC 20.

Hummer: LSU is averaging 55 points per game thus far. Vanderbilt is averaging 15 points per game. Give me the Tigers to win and to cover. The Commodores can’t keep up. (How weird is that to say with LSU?) … LSU 45, Vanderbilt 17.

Crawford: The dreaded 0-3 start for the Commodores. This certainly isn't what Derek Mason wanted, but it's going to happen. Joe Burrow continues his march at the top of the Heisman leaderboard alongside Tua and Jalen with several touchdown passes. But, Vanderbilt performs admirably and covers in this spot .. LSU 41, Vanderbilt 20.

Hummer: The best quote of the week goes to Red Hawks head coach Chuck Martin who said of playing Ohio State: “It’s kind of like going to recess and they have the first 85 picks.” Spot on. But I still like Miami to cover. The Red Hawks have done so in eight of their last 10 games. … Ohio State 48, Miami (Ohio) 10.

Crawford: Admittedly, I chose this game this week because Ohio State is a national championship contender with lots of eyes wanting to see the Buckeyes this season and I feel there's some value on potentially taking the underdog to cover. Why? Ohio State is a second-half flurry from FAU from being 3-0 against the spread this fall, which has surprised everyone considering Justin Fields has taken over the offense without expected hiccups. Is this the week the Buckeyes hit somewhat of a lull after a big win at Indiana? With the trip to Nebraska coming next Saturday, take Miami and the points. .. Ohio State 45, Miami (Ohio) 7.

Hummer: Maybe I’m missing something here, but this line seems really aggressive for Missouri. I get that the Tigers are at home and the Gamecocks haven’t been as good as advertised, but didn’t South Carolina just play pretty well against Alabama? This was a two-point game a year ago, I expect it to be similarly close in 2019. … Missouri 38, South Carolina 34.

Crawford: One of the games I would play officially on my own in Week 4, I love the Gamecocks in this spot. I think South Carolina managed to seize confidence in last week's loss to Alabama and may have changed its mindset on how it approaches the rest of the season offensively. The staff is is confident in freshman quarterback Ryan Hilinski and while this is his first road start, nearly 10 points is a lot to give a team that nearly hit 500 yards total offense vs. Alabama. Big game for Will Muschamp and I think the season starts to shift for the road team .. South Carolina 31, Mizzou 27.

Hummer: The Tigers have been up and down early in 2019 despite their 3-0 record, a pace largely dependent on the play of true freshman starter Bo Nix. The five-star’s looked brilliant in some moments but overall has a completion percentage of just 52.4 percent. This will be his first true road start of his career, and I think that makes the difference. … Texas A&M 27, Auburn 21.

Crawford: This one feels like a sucker bet and I'll go ahead and grab Auburn and the points. These are two evenly-matched teams and while the coaching edge falls in Texas A&M's favor, I wouldn't discount the likelihood that the Tigers control this game at the line of scrimmage. I'm not picking Bo Nix and Auburn to win outright, but if you're betting on it, take the four. .. Texas A&M 27, Auburn 24.

Hummer: Oklahoma State’s been a good measuring stick for Texas during Mike Gundy’s regime. Recently, the answer has been: Not good enough. The Cowboys have won four straight in this series and seven of the last nine. Hindi ebooks download. That changes this week. Texas is ready to contend for a Big 12 title, and it proves it against the Cowboys. The Longhorns’ defense makes the difference. … Texas 38, Oklahoma State 28.

Biggest College Games This Weekend

Crawford: You know, I'd be inclined to lean upset here if this game was in Stillwater, but night game in Austin means the home crowd should be in a frenzy and I like the Longhorns' defense this fall against teams not named LSU. Oklahoma State has elite-level weapons at WR and RB and will score points, but Texas is the team on a mission and I'd lean Longhorns cover in this spot. .. Texas 41, Oklahoma State 30.

Hummer: Give me 39 points and I’m usually going to pick a team to cover. That includes Southern Miss, which is playing pretty well early this year. The Golden Eagles just went on the road and dropped 47 points on Troy in a win. Alabama gets up big early but takes its foot off the gas late. … Alabama 52, Southern Miss 14.

Crawford: Guess what? The Crimson Tide will run the football on Saturday and they'll do it with success. Alabama covering is a dangerous proposition this season, but I'm sensing it happens on Saturday afternoon in Tuscaloosa whether Nick Saban likes an 11 a.m. local kick or not. .. Alabama 52, Southern Miss 7.

Hummer: This is a toss-up game and we have very little to go by here for either program. Wisconsin’s looked better early in 2019, but Jack Coan remains untested under center. Michigan’s struggled, especially offensively, but it’s talented enough to reach the playoff. I picked the Wolverines as my Big Ten champ, so I might as well go down with the ship. … Michigan 24, Wisconsin 21.

Crawford: One game I don't feel strongly about in either direction, I'll lean with historical data here and take Wisconsin in an ugly, defensive-minded struggle for both teams. Jonathan Taylor eclipses 100 yards and scores a late touchdown as the jeers for Jim Harbaugh grow a little louder. .. Wisconsin 24, Michigan 22.

Hummer: I’m not sure what to make of either of these programs at the moment. Florida is starting a backup QB and hasn’t looked like a top 10 team yet. Meanwhile, Tennessee lost to Georgia State. One is worse, but I actually like the points here with the Vols. They looked better in Week 3, and I think they’re ready to go for the Gators. … Florida 24, Tennessee 18.

Week 4 College Football Spreads

Crawford: I'm putting the Gators on upset alert this week, not because I think Tennessee is the better team, but I'm not sure how this Florida offense is going to respond to Kyle Trask as the starter. It's been a long time since the Vols have beaten one of their arch rivals as a double-digit underdog, but this matchup intrigues me. If the line moves higher than 14, this will be an official play on Tennessee .. Florida 27, Tennessee 20.

Hummer: That’s a pretty disrespectful line for Notre Dame. I know the Irish have some flaws and haven’t been great against elite competition, but come on now. Notre Dame isn’t going to win, but they keep it close for three quarters. … Georgia 31, Notre Dame 21.

Crawford: If you can get this game under 14, pound the Georgia cover. While I'm a believer in Ian Book, I'm not at all certain that the Irish can establish a rushing attack in this spot, which is what they'll need to combat the Bulldogs' flurry of punches. Georgia has shown next to nothing from the offensive playbook over the first three weeks, so I'm interested in seeing something a little less vanilla on Saturday night. I'll take the cover, but again, I'd prefer -13.5 here .. Georgia 34, Notre Dame 17.